2/11/2023 0 Comments E with tilde and breveMMSE scores were significantly increased during the intervention by mixed model Dunnett's test and Wilcoxon signed-rank tests (+1.7, P < 0.01). Of the 27 participants enrolled, 19 completed the study. Mental condition and quality of life for gastrointestinal symptoms were measured using the Profile of Mood States 2nd Edition (POMS2), and the Gastrointestinal Symptom Rating Scale (GSRS). breve A1 on elderly with MCI in Aki Orthopedics Rehabilitation Clinic in Japan.Ģ7 participants were screened by their Mini Mental State Examination (MMSE) scores.Ĭognitive function was assessed using MMSE and Digit Symbol Substitution Test (DSST) at baseline and every 8 weeks. We conducted an open-label, single-arm study to examine the effects of 24-week supplementation of B. breve A1) for preventing cognitive impairment in Alzheimer's disease model mice, which suggested that supplementation of the probiotics could be an effective therapeutic strategy for managing cognitive function in mild cognitive impairment (MCI). We previously reported the therapeutic potential of Bifidobacterium breve A1 (B.
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